BECLIN

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes ...

Mol Biol Cell. 2008 Dec;19(12):5360-72. doi: 10.1091/mbc.E08-01-0080. Epub 2008 Oct 8. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes ...

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BECN1 - Wikipedia

Beclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene 6 (Atg6) and BEC-1 ...

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Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally ...

Nat Cell Biol. 2009 Apr;11(4):385-96. doi: 10.1038/ncb1846. Epub 2009 Mar 8. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate ...

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BECN1 - Beclin-1 - Homo sapiens (Human) - BECN1 gene & protein

Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.2 ...

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Beclin 1 Antibody (NB500-249): Novus Biologicals

Rabbit Polyclonal Anti-Beclin 1 Antibody cited in 104 publications. Validated: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD. Tested Reactivity: Human ...

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Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration ...

29 Dec 2019 ... Proteolytic cleavage of Beclin 1 was characterized in lysates of human AD brain samples. We developed viral tools allowing for the selective ...

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Tat-Beclin 1 D11 Autophagy Inducing Peptide - Retroinverso form ...

Tat-D11 [NBP2-49888]: peptides comprising 11 amino acids derived from Beclin 1 linked to the HIV Tat protein with a diglycine linker. These peptides are in the ...

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Human/Mouse Beclin 1 Antibody AF5295: R&D Systems

Detection of Human/Mouse Beclin 1 by Western Blot. Western blot shows lysates of T47D human breast cancer cell line, HeLa human cervical epithelial ...

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Tat-Beclin 1 L11 Autophagy Inducing Peptide (NBP2-49886): Novus ...

Western Blot: Tat-Beclin 1 L11 Autophagy Inducing Peptide [NBP2-49886] - WB analysis of lysates from HeLa cells that were left untreated (blank) or were ...

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Beclin-1 polyclonal antibody - ADI-905-721 - Enzo Life Sciences

Host: Rabbit. Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of human Beclin-1. UniProt ID: Q14457. Species reactivity ...

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Beclin-1 Antibody - CST

Polyclonal Antibody for studying Beclin 1 in the Autophagy Signaling research area.

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Beclin 1 Is Required for Neuron Viability and Regulates Endosome ...

2 Oct 2014 ... Abstract. Deficiency of autophagy protein beclin 1 is implicated in tumorigenesis and neurodegenerative diseases, but the molecular ...

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Beclin 1 Is Required for Starvation-Enhanced, but Not Rapamycin ...

31 Oct 2012 ... Beclin 1 is critical for starvation-induced LAP but not for rapamycin-induced LAP. We have shown previously that B. pseudomallei is susceptible ...

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Physiological functions of Atg6/Beclin 1: a unique autophagy-related ...

25 Sep 2007 ... In many cases, the role of autophagy is identified through studies of an autophagy-related protein, Atg6/Beclin 1. This protein is part of a lipid ...

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Beclin 1 - an overview | ScienceDirect Topics

Beclin 1 is a core component of Beclin 1-PI3KC3 complex, a lipid-kinase ... In many cases, Beclin 1-mediated autophagy inhibits apoptosis and promotes ...

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Beclin 1, an autophagy-related gene, augments apoptosis in U87 ...

10 Feb 2014 ... Beclin 1 acts as a tumor suppressor and is an essential mediator of autophagy. Beclin 1 also interacts with Bcl-2 and can induce apoptosis by ...

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Beclin 1 elisa kit

Buy Beclin 1 elisa kit, Human Beclin 1 ELISA Kit-AAD27650.1 (MBS732891) product datasheet at MyBioSource, ELISA Kits.

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Phospho-Beclin-1 (Ser15) (D4B7R) Rabbit mAb - CST

Monoclonal Antibody for studying Beclin 1 (Ser15) phosphate in the Autophagy Signaling research area.

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Beclin-1 (D40C5) Rabbit mAb

Beclin-1 (D40C5) Rabbit mAb rev. 01/11/16. W, IP. Endogenous. H, M, R, Mk. 60 kDa. Rabbit IgG**. Background: Autophagy is a catabolic process for the au-.

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Anti-Beclin 1 antibody [OTI4A10] (ab118148) | Abcam

Mouse monoclonal Beclin 1 antibody [OTI4A10]. Validated in WB, Flow Cyt, ICC/ IF and tested in Human. Cited in 1 publication(s). Immunogen corresponding to ...

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Why doesn't Beclin 1, a BH3-only protein, suppress the anti ...

7 May 2009 ... Beclin 1 binds to Bcl-2 through its BH3 domain and this interaction inhibits starvation-induced autophagy. However, we have found that when ...

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JCI Insight - Beclin-1 regulates cigarette smoke–induced kidney ...

20 Sep 2019 ... Beclin-1 regulates cigarette smoke–induced kidney injury in a murine model of chronic obstructive pulmonary disease. Maria A. Pabón,1,2 ...

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Anti-Beclin 1 Antibodies | Invitrogen

25 results ... 49 antibodies to Beclin 1 and validated for use in 5 applications ( Immunohistochemistry,Flow Cytometry,Western Blot,Immunocytochemistry ...

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Identification of Barkor as a mammalian autophagy-specific factor for ...

9 Dec 2008 ... Notably, Beclin 1 and PI3KC3 have pleiotropic functions in multiple cellular processes. PI3KC3 is not only required for autophagy, but also has ...

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Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled ...

15 Aug 2013 ... Here, we identified a previously uncharacterized mammalian-specific protein, Beclin 2, which, like Beclin 1, functions in autophagy and ...

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Beclin-1 as a neutrophil-specific immune checkpoint - JCI

28 Oct 2019 ... A model for the interaction between Becn1- deficient neutrophils and B cells or B cell leukemia/lymphoma cells in vivo shows beclin-1 ...

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Beclin 1 Antibody 11306-1-AP | Proteintech

Beclin 1 antibody Rabbit Polyclonal from Proteintech validated in Western Blot ( WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), ...

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Beclin 2 Regulates G Protein-Coupled Receptor Degradation and ...

1 Oct 2013 ... Major finding: Beclin 2 is a Beclin 1 homolog that also mediates G protein- coupled receptor (GPCR) degradation. Mechanism: Beclin 2 ...

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Autophagy-Independent Role for Beclin 1 in the Regulation of ...

15 Jan 2019 ... two autophagy genes, ATG5 and Beclin 1, revealed different ... endosome maturation that is regulated by Beclin 1, the transition of APPL1-.

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The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate ...

18 Feb 2019 ... Beclin 1 is also known to prevent the growth of malignant tumors. Wei, An et al. found that to do so, Beclin 1 must have a phosphate group ...

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Beclin 1 Phosphorylation – at the Center of Autophagy ... - Frontiers

12 Oct 2019 ... Beclin 1 was originally identified as a yeast two-hybrid interaction partner of the anti-apoptotic protein – BCL2 (Liang et al., 1998). Soon after ...

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Overexpression of the autophagic beclin-1 protein clears mutant ...

data demonstrate that autophagy is a key degradation pathway, with beclin-1 playing a ... of the autophagic protein 6/beclin-1 (Atg6/beclin-1) or inhibition.

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Tat-Beclin-1

Peptides , Cell Permeable Peptides (CPP) , Drug Delivery Peptides , Tat-Beclin-1 ; Beclin-1 peptide is the HIV-1 Nef binding portion of full-length human Beclin-1 ...

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Purified anti-Beclin-1

30 May 2019 ... Beclin-1 plays a central role in autophagy and is involved in autophagosome formation. It acts as core subunit of the PI3K complex that ...

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Intestinal epithelial tight junction barrier regulation by autophagy ...

1 May 2019 ... Autophagy-related protein-6 (ATG6/beclin 1), a key protein in the ... The constitutive role of beclin 1 in the intestinal TJ barrier is not known.

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Beclin-1-Dependent Autophagy Protects the Heart During Sepsis ...

24 Jul 2019 ... Beclin-1-dependent autophagy in the heart during sepsis and the potential therapeutic benefit of targeting this pathway were investigated in a ...

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Beclin-1 (ab1) antibody | Western, ELISA, Immunocytochemistry ...

Tested Applications: Western, ELISA, Immunocytochemistry. Rabbit polyclonal Beclin-1 (ab1) antibody. 100% Bioguaranteed.

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Anti-Beclin 1 antibody (GTX133555) | GeneTex

Rabbit Polyclonal Beclin 1 antibody. Validated in WB, IHC-P. Tested in Human. Cited in 1 reference(s).

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Anti-Beclin 1 Antibody Products | Biocompare.com

1265 products ... Anti-Beclin 1 antibodies are available from several suppliers. In humans, this protein is encoded by the gene BECN1. The protein may also be ...

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MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages

28 Nov 2008 ... Beclin 1, the mammalian homologue of yeast Atg6, is a key component of a class III phosphatidylinositol 3-kinase complex that initiates ...

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